Radiomics signature: A potential biomarker for β-arrestin1 phosphorylation prediction in hepatocellular carcinoma

doi:10.3748/wjg.v28.i14.1479

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Apr 14, 2022 (publication date) through Nov 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 14, 2022; 28(14): 1479-1493
Published online Apr 14, 2022. doi: 10.3748/wjg.v28.i14.1479

Table 3 Diagnostic performance of the three models for predicting β-arrestin1 phosphorylation-positive hepatocellular carcinoma

	Training group				Validation cohort
	AUC (95%CI)	SPE	SEN	P value	AUC (95%CI)	SPE	SEN	P value
RS	0.754 (0.640-0.868)	53.8	86.7	0.007¹	0.704 (0.454-0.953)	47.6	77.8	0.791¹
CR	0.794 (0.686-0.901)	87.2	66.7	0.631²	0.646 (0.411-0.880)	81.0	33.3	0.713²
CRR	0.898 (0.820-0.977)	87.2	86.7	0.011³	0.735 (0.505-0.966)	71.4	66.7	0.147³

¹AUCs of the radiomics score and clinico-radiological-radiomics model were compared.

²AUCs of the radiomics score and clinico-radiological model were compared.

³AUCs of the clinico-radiological model and clinico-radiological-radiomics model were compared.

RS: Radiomics score; CR: Clinico-radiological; CRR: Clinico-radiological-radiomics; SEN: Sensitivity; SPE: Specificity; AUC: Area under the curve; CI: Confidence interval.

Citation: Che F, Xu Q, Li Q, Huang ZX, Yang CW, Wang LY, Wei Y, Shi YJ, Song B. Radiomics signature: A potential biomarker for β-arrestin1 phosphorylation prediction in hepatocellular carcinoma. World J Gastroenterol 2022; 28(14): 1479-1493
URL: https://www.wjgnet.com/1007-9327/full/v28/i14/1479.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i14.1479