Increased prognostic value of clinical–reproductive model in Chinese female patients with esophageal squamous cell carcinoma

doi:10.3748/wjg.v28.i13.1347

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 7, 2022; 28(13): 1347-1361
Published online Apr 7, 2022. doi: 10.3748/wjg.v28.i13.1347

Table 2 Comparison of three models in primary training, internal validation, and external validation sets

	Primary training set		Internal validation set		External validation set
	C-index (95%CI)	P value	C-index (95%CI)	P value	C-index (95%CI)	P value
Full model	0.701 (0.655-0.746)	Ref.	0.684 (0.619-0.748)	Ref.	0.672 (0.609-0.734)	Ref.
Clinical-model	0.629 (0.578-0.681)	0.000	0.593 (0.531-0.655)	0.009	0.589 (0.514-0.663)	0.014
TNM stage	0.638 (0.576-0.699)	0.013	0.552 (0.462-0.641)	0.011	0.560 (0.462-0.657)	0.033

Full model: Pregnancy number + menopausal age + estrogen receptor alpha + estrogen receptor beta + N stage + differentiation + diagnose age + incidence area; Clinical model: N stage + differentiation + diagnose age+ incidence area; CI: Confidence interval; TNM stage: Tumor-node-metastasis stage; N: Lymph node metastasis.

Citation: Zhang DY, Ku JW, Zhao XK, Zhang HY, Song X, Wu HF, Fan ZM, Xu RH, You D, Wang R, Zhou RX, Wang LD. Increased prognostic value of clinical–reproductive model in Chinese female patients with esophageal squamous cell carcinoma. World J Gastroenterol 2022; 28(13): 1347-1361
URL: https://www.wjgnet.com/1007-9327/full/v28/i13/1347.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i13.1347