Quercetin exerts anti-inflammatory effects via inhibiting tumor necrosis factor-α-induced matrix metalloproteinase-9 expression in normal human gastric epithelial cells

Figure 1 Identification studies of matrix metallopeptidase-9, a potential inflammation-related protein involved in gastric cancer. A: Identification of potential inflammation-related proteins involved in gastric cancer (GC) based on an omics approach including four integrated datasets. The strategy included proteomic profiling; B: Relative expression levels of matrix metallopeptidase-9 in paired GC and adjacent normal tissues in humans and mice. A t test was used for comparisons between the two groups. Data are expressed as the mean ± SEM of three independent experiments. ^aP < 0.05, ^bP < 0.01 vs controls. GC: Gastric cancer; GEO: Gene Expression Omnibus; MMP-9: Matrix metallopeptidase-9; NCBI: National Center for Biotechnology Information.