Assessment of pathogens and risk factors associated with bloodstream infection in the year after pediatric liver transplantation

Table 1 Demographics and details of pediatric liver transplantation

Characteristics	Total n = 378, n (%) or median (IQR)
Primary LDLT: DDLT	287 (76): 91 (24)
Age, year	1.58 (0.83-5.42)
Male: Female	176 (47): 202 (53)
Height, z-score	-0.79 (-1.81-0.27)
Weight, z-score	-0.23 (-1.13-0.62)
Growth failure	94 (25)
Indications
Biliary atresia	200 (53)
Acute liver failure	88 (23)
Metabolic liver	45 (12)
Malignancy	25 (6.6)
Other liver disease	20 (5.3)
Urgency of LT
PELD	15.4 (10.6-23.2)
MELD	27.4 (23-29)
Ventilator	25 (6.6)
Renal replacement	19 (5)
Liver support system	20 (5.3)
Graft type
LDLT, including dual LT	287 (76)
DDLT split	54 (14)
DDLT whole liver	37 (10)
ABO incompatible	11 (3)
Graft-recipient weight ratio, %	2.5 (1.69-3.22)
Total operation time, hours	6.9 (5.9-8.8)
Volume of RBC transfusion, cc/kg	19.2 (7.7-33.3)
Post-LT hospital stay, days	36 (26-51)
Surgical complication
Hepatic artery	4 (1.1)
Portal vein	51 (13)
Hepatic vein	39 (10)
Bile duct	21 (5.6)
Re-operation	50 (13)
Cytomegalovirus infection	222 (59)
Epstein–Barr virus infection	259 (69)
Post-transplant lymphoproliferative disorder	14 (3.7)
Acute cellular rejection	186 (49)
Chronic rejection	19 (5)
Patients with ≥ 1 BSI episode	106 (28)
Total BSI cases	162 (1.5 times per patient)
Graft loss	58 (15)
Patient loss	34 (9)

BSI: Blood stream infection; DDLT: Deceased donor liver transplantation; IQR: Interquartile range; LDLT: Living donor liver transplantation; MELD: Model for End-Stage Liver Disease; PELD: Pediatric End-Stage Liver Disease.