Diagnostic performance of endoscopic classifications for neoplastic lesions in patients with ulcerative colitis: A retrospective case-control study

Figure 1 Endoscopic features of ulcerative colitis-associated neoplasms misdiagnosed by all endoscopists. A: White-light imaging reveals a flat elevated lesion in the rectum; B: Chromoendoscopy with indigo carmine shows a clear lesion border; C: Magnifying endoscopy with narrow-band imaging of box in (B) shows regular surface and vascular patterns, which were classified by all endoscopists as Japan Narrow-Band Imaging Expert Team classification type 2A; D: Magnifying endoscopy with crystal violet chromoendoscopy of box in (B) reveals relatively uniform villous structures, which were classified by all endoscopists as pit pattern type IV; E: Pathological examination of the resected specimen by endoscopic submucosal dissection shows architectural atypia. This lesion was pathologically diagnosed as high-grade dysplasia (hematoxylin and eosin staining, original magnification × 50); F: Immunohistochemistry for p53 on serial section of (E).