Gut dysbiosis and small intestinal bacterial overgrowth as independent forms of gut microbiota disorders in cirrhosis

Table 4 Abundance of bacteria at the genus level in gut microbiome of patients with and without small intestinal bacterial overgrowth

Genus	Family	Patients with SIBO (n = 24)	Patients without SIBO (n = 23)	P value
Blautia	Lachnospiraceae	13.38 (6.78-20.52)	6.99 (3.22-13.47)	0.020
Faecalibacterium	Ruminococcaceae	8.64 (3.65-19.55)	7.82 (3.02-12.74)	0.516
Gemmiger	Ruminococcaceae	2.33 (0.95-4.69)	1.65 (0.03-2.86)	0.237
Ruminococcus	Ruminococcaceae	1.80 (0.01-3.51)	0.58 (0.12-1.83)	0.617
Roseburia	Lachnospiraceae	1.66 (0.51-4.20)	0.92 (0.13-3.42)	0.377
Streptococcus	Streptococcaceae	1.36 (0.22-5.78)	0.37 (0.08-3.42)	0.151
Dorea	Lachnospiraceae	1.18 (0.63-2.51)	0.69 (0.42-1.35)	0.099
Bacteroides	Bacteroidaceae	1.15 (0.34-3.04)	3.59 (1.08-5.05)	0.012
Fusicatenibacter	Lachnospiraceae	0.79 (0.27-1.06)	0.13 (0.04-0.31)	0.003
Prevotella	Prevotellaceae	0.43 (0.01-2.27)	0.12 (0.01-2.19)	0.856
Escherichia	Enterobacteriaceae	0.38 (0.01-1.64)	0.28 (0.01-1.31)	0.890
Bifidobacterium	Bifidobacteriaceae	0.32 (0.11-1.15)	0.47 (0.07-2.39)	0.413
Oscillibacter	Oscillospiraceae	0.07 (0.01-0.15)	0.21 (0.09-0.38)	0.025
Alistipes	Rikenellaceae	0.06 (0.01-0.52)	0.41 (0.06-1.25)	0.025
Anaerostipes	Lachnospiraceae	0.62 (0.06-0.50)	0.49 (0.08-0.67)	0.170
Parabacteroides	Porphyromonadaceae	0.03 (0.00-0.11)	0.16 (0.05-0.29)	0.009
Acinetobacter	Moraxellaceae	0.03 (0.02-0.05)	0.02 (0.01-0.03)	0.004
Akkermansia	Akkermansiaceae	0.01 (0.00-0.71)	0.01 (0.00-1.33)	0.983
Oribacterium	Lachnospiraceae	0.01 (0.00-0.02)	0.00 (0.00-0.00)	0.040
Barnesiella	Porphyromonadaceae	0.00 (0.00-0.03)	0.03 (0.00-0.06)	0.025
Intestinimonas	Oscillospiraceae	0.00 (0.00-0.02)	0.03 (0.01-0.06)	0.015
Haemophilus	Pasteurellaceae	0.00 (0.00-0.10)	0.00 (0.00-0.01)	0.031

Genera with an abundance of < 1% and not significantly different between patient groups are not presented. SIBO: Small intestinal bacterial overgrowth.