Gut dysbiosis and small intestinal bacterial overgrowth as independent forms of gut microbiota disorders in cirrhosis

Table 3 Abundance of bacteria at the family level in gut microbiome of patients with and without small intestinal bacterial overgrowth

Family	Patients with SIBO (n = 24)	Patients without SIBO (n = 23)	P value
Families of Clostridia
Lachnospiraceae	41.00 (29.71-55.82)	31.30 (17.55-43.85)	0.047
Ruminococcaceae	26.15 (13.79-35.50)	21.41 (14.89-34.43)	0.856
Peptostreptococcaceae	0.50 (0.18-2.72)	0.17 (0.04-1.13)	0.066
Clostridiaceae	0.30 (0.01-1.12)	0.10 (0.01-0.47)	0.463
Eubacteriaceae	0.00 (0.00-0.00)	0.00 (0.00-0.01)	0.463
Families of Bacilli
Streptococcaceae	1.46 (0.29-6.03)	0.41 (0.10-3.42)	0.170
Lactobacillaceae	0.23 (0.03-0.56)	0.10 (0.01-0.38)	0.413
Staphylococcaceae	0.02 (0.01-0.03)	0.01 (0.01-0.02)	0.450
Enterococcaceae	0.01 (0.00-0.04)	0.01 (0.00-0.23)	0.873
Family of Negativicutes
Veillonellaceae	0.43 (0.07-0.73)	0.16 (0.05-1.15)	0.632
Families of Bacteroidetes
Bacteroidaceae	1.13 (0.35-3.19)	3.77 (1.05-4.96)	0.014
Prevotellaceae	0.56 (0.01-3.12)	0.27 (0.04-3.07)	0.941
Porphyromonadaceae	0.11 (0.02-0.29)	0.40 (0.23-0.66)	0.002
Rikenellaceae	0.07 (0.01-0.74)	0.45 (0.06-1.35)	0.047
Families of Proteobacteria
Enterobacteriaceae	0.72 (0.02-2.13)	1.51 (0.05-2.81)	0.632
Moraxellaceae	0.04 (0.02-0.05)	0.02 (0.01-0.04)	0.014
Pasteurellaceae	0.01 (0.00-0.15)	0.00 (0.00-0.01)	0.025
Sutterellaceae	0.01 (0.00-0.06)	0.02 (0.00-0.05)	0.400
Desulfovibrionaceae	0.00 (0.00-0.01)	0.01 (0.00-0.03)	0.042
Families of Actinobacteria
Bifidobacteriaceae	0.46 (0.14-1.50)	0.65 (0.12-3.22)	0.366
Coriobacteriaceae	0.09 (0.07-0.14)	0.08 (0.04-0.20)	0.790
Actinomycetaceae	0.02 (0.01-0.04)	0.01 (0.00-0.03)	0.039
Micrococcaceae	0.02 (0.01-0.06)	0.01 (0.00-0.01)	0.045

SIBO: Small intestinal bacterial overgrowth.