Diagnostic performance of endoscopic classifications for neoplastic lesions in patients with ulcerative colitis: A retrospective case-control study

Table 4 Diagnostic performance (95% confidence interval) for each type in the pit pattern classification

	Sensitivity, (%)	Specificity, (%)	PPV, (%)	NPV, (%)	Accuracy, (%)
UCAN pit pattern type III/IV
Experts	100 (37.3–100)	84.2 (77.6–84.2)	40.0 (14.9–40.0)	100 (92.2–100)	85.7 (73.8–85.7)
Non-experts	100 (36.4–100)	57.9 (51.2–57.9)	20.0 (7.3–20.0)	100 (88.4–100)	61.9 (49.8–61.9)
UCAN pit pattern type VI low irregularity
Experts	50.0 (35.2–59.8)	71.4 (41.9–91.0)	77.8 (54.8–93.0)	41.7 (24.4–53.1)	57.1 (37.5–70.2)
Non-experts	42.9 (28.4–48.7)	85.7 (56.7–97.3)	85.7 (56.7–97.3)	42.9 (28.4–48.7)	57.1 (37.8–64.9)
UCAN pit pattern type VI high irregularity/VN
Experts	60.0 (26.1–85.8)	81.3 (70.7–89.3)	50.0 (21.8–71.5)	86.7 (75.4–95.3)	76.2 (60.1–88.5)
Non-experts	60.0 (27.5–75.9)	93.8 (83.6–98.7)	75.0 (34.4–94.9)	88.2 (78.7–92.9)	85.7 (70.3–93.3)
SN pit pattern type III/IV
Experts	87.5 (75.6–87.5)	100 (72.8–100)	100 (86.4–100)	77.8 (56.6–77.8)	91.3 (74.8–91.3)
Non-experts	81.3 (68.1–86.3)	85.7 (55.6–97.3)	92.9 (77.8–98.6)	66.7 (43.3–75.6)	82.6 (64.3–89.6)
SN pit pattern type VI low irregularity
Experts	100 (63.4–100)	83.3 (73.2–83.3)	62.5 (39.6–62.5)	100 (87.8–100)	87.0 (71.0–87.0)
Non-experts	60.0 (26.0–85.9)	83.3 (73.9–90.5)	50.0 (21.7–71.6)	88.2 (78.2–95.8)	78.3 (63.5–89.5)
SN pit pattern type VI high irregularity/VN
Experts	50.0 (11.2–50.0)	100 (96.3–100)	100 (22.4–100)	95.5 (91.9–95.5)	95.7 (88.9–95.7)
Non-experts	50.0 (10.2–85.6)	95.2 (91.4–98.6)	50.0 (10.2–85.6)	95.2 (91.4–98.6)	91.3 (84.4–97.5)

CI: Confidence interval; NPV: Negative predictive value; PPV: Positive predictive value; SN: Sporadic neoplasms; UCAN: Ulcerative colitis-associated neoplasms.