Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer

Figure 4 Fork head box M1 promoted gallbladder cancer cell proliferation and metastasis via vascular endothelial growth factor-A. A-C: Hematoxylin-eosin staining, immunohistochemical staining of fork head box M1 and vascular endothelial growth factor-A (VEGF-A) in gallbladder cancer tissues (scale bars: 100 μm); D: Correlation between fork head box M1 and VEGF-A analyzed according to fluorescence score; E-H: Relative protein expression of VEGF-A; I: Luciferase assay of fork head box M1 and VEGF-A. ^aP < 0.05, ^bP < 0.01. FoxM1: Fork head box M1; VEGF-A: Vascular endothelial growth factor-A; NC: Normal control.