Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer

Figure 3 Fork head box M1 influenced migration and invasion of gallbladder cancer cells in vitro. A-D: Lenti-fork head box M1-transfected cells had stronger migration and invasion abilities (cell invasion and migration assays, scale bars: 200 μm); E and F: Knockdown-fork head box M1 cells increased apoptotic levels (apoptosis assay); G and H: Upregulated fork head box M1 significantly enhanced vessel generation ability (endothelial cell tube formation assay, scale bars: 100 μm). ^aP < 0.05, ^bP < 0.01. FoxM1: Fork head box M1.