Meta-Analysis
Copyright ©The Author(s) 2021.
World J Gastroenterol. Feb 28, 2021; 27(8): 737-750
Published online Feb 28, 2021. doi: 10.3748/wjg.v27.i8.737
Table 2 Meta-analysis results for the relationship between lymph node metastasis and clinicopathological factors in T1 esophageal squamous cell carcinoma patients
Factors
Studies
Patients
Heterogeneity I2 (P value)
Pooled OR (95%CI)
P value
Age (continuous) (yr)6157122% (0.27)-0.81 (-1.75-0.14)0.10
Sex (male/female)1229130% (0.78)1.16 (0.91-1.48)0.23
Tumor size (> 2/≤ 2) (cm)614820% (0.74)1.93 (1.49-2.50)< 0.001a
Tumor location (L/U-M)1022910% (0.57)1.46 (1.17-1.82)< 0.001a
T1 substage (T1b/T1a)1535580% (0.87)6.28 (4.93-8.00)< 0.001a
Differentiation (G3/G1-2)1119660% (0.49)2.11 (1.64-2.72)< 0.001a
LVI (present/absent)11222640% (0.08)5.86 (4.60-7.48)< 0.001a
Macroscopic type (nonflat/flat)6121335% (0.17)3.17 (2.33-4.31)< 0.001a
INF (present/absent)35910% (0.66)1.82 (0.89-3.73)0.10