Circular RNA circVAPA promotes chemotherapy drug resistance in gastric cancer progression by regulating miR-125b-5p/STAT3 axis

Figure 1 CircVAPA enhances proliferation and represses apoptosis of gastric cancer cells. A: The expression of circVAPA was measured by qPCR in the gastric cancer tissues (n = 50) and adjacent normal tissues (n = 50); B-G: SGC7901 and HGC27 cells were treated with the circVAPA shRNA or control shRNA. Cell viability was tested by MTT assay (B and C), cell proliferation was measured by colony formation assay (D and E), and cell apoptosis was analyzed by flow cytometry (F and G). Data are presented as the mean ± SD. ^bP < 0.01.