Washed microbiota transplantation reduces proton pump inhibitor dependency in nonerosive reflux disease

Table 3 Clinical responses to washed microbiota transplantation in patients with nonerosive reflux disease

Item		WMT, n = 15
Remission1, n		14 (93.3)
Remission after the first course of WMT, n		13 (86.7)
Remission after the first course of FMT until the end of the study, n		10 (66.7)
No remission after the first course of WMT, n		2 (13.3)
Recurrence after remission, n		2 (13.3)
Side effects of WMT treatment2, n	No	14 (93.3)
	Yes	1 (6.70)

¹The scores of the reflux disease questionnaire or gastroesophageal reflux disease questionnaire at 1 mo post-washed microbiota transplantation (WMT) were reduced by 30%.

²Only one of the 15 patients had minor side effects, with a mushy stool two or three times a day, which resolved on their own after 1 wk, but no abdominal pain, black stool, fever, or serious WMT-related side effects were observed.

WMT: Washed microbiota transplantation; FMT: Fecal microbiota transplantation.