Copyright
©The Author(s) 2021.
World J Gastroenterol. Feb 14, 2021; 27(6): 501-512
Published online Feb 14, 2021. doi: 10.3748/wjg.v27.i6.501
Published online Feb 14, 2021. doi: 10.3748/wjg.v27.i6.501
Table 1 Baseline characteristics and performance of each serum tumor maker in predicting advanced cystic mucinous neoplasms
Overall | Benign | Advanced | P value1 | |
Patients characteristics (n = 187) | ||||
Male (n, %) | 109 (58.3) | 63 (54.8) | 46 (63.9) | 0.007 |
Age (Median, IQR) | 62 (54-68) | 61 (51-68) | 63.5 (56-70) | 0.014 |
Cyst size (Median, IQR, mm) | 28.5 (19-42) | 24.5 (15-37) | 38.5 (28-59.5) | < 0.0001 |
Location (H/B/T/D) | 111/31/30/15 | 63/20/20/10 | 48/11/10/5 | |
CA19-9 (n = 187) | ||||
Median, IQR (U/mL) | 10.11(4.4-52.9) | 7.1(3.4-16.3) | 55.5 (9.3-319.3) | < 0.0001 |
≥ 37/< 37 U/mL | 50/137 | 11/104 | 39/33 | < 0.0001 |
CEA (n = 187) | ||||
Median, IQR (ng/mL) | 2.37 (1.54-3.98) | 2.23 (1.5-3.3) | 3.1 (2.02-5.2) | < 0.0001 |
≥ 5/< 5 ng/mL | 27/160 | 9/106 | 18/54 | 0.001 |
CA125 (n = 135) | ||||
Median, IQR (U/mL) | 12.2 (8.2-18.8) | 12.1 (7.0-16.8) | 12.75 (8.9-23.4) | 0.002 |
≥ 35 /< 35 U/mL | 10/125 | 1/82 | 9/43 | 0.002 |
CA724 (n = 116) | ||||
Median, IQR (U/mL) | 1.6 (1.025-3.15) | 1.44 (1.0-2.66) | 2.4 (1.07-6.8) | 0.014 |
≥ 9.8/< 9.8 U /mL | 10/106 | 3/70 | 7/36 | 0.05 |
CA242 (n = 31) | ||||
Median, IQR (U/mL) | 7.13 (3.6-12.7) | 5.35 (2.7-7.9) | 11.1 (6.95-31.7) | 0.136 |
≥ 20/< 20 U/mL | 6/25 | 1/15 | 5/10 | 0.08 |
- Citation: Sun LQ, Peng LS, Guo JF, Jiang F, Cui F, Huang HJ, Jin ZD. Validation of serum tumor biomarkers in predicting advanced cystic mucinous neoplasm of the pancreas. World J Gastroenterol 2021; 27(6): 501-512
- URL: https://www.wjgnet.com/1007-9327/full/v27/i6/501.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i6.501