Magnetic challenge against gastroesophageal reflux

Table 2 Comparison of magnetic sphincter augmentation and fundoplication

	Aiolfi et al[18]					Skubleny et al[19]			Riegler et al[20]			Reynolds et al[21]				Guidozzi et al[22]			Warren et al[23]
	MSA	FUNDO			P value	MSA	FUNDO	P value	MSA	FUNDO	P value		MSA	FUNDO	P value	MSA	FUNDO	P value	MSA	FUNDO	P value
Type of study	Systematic review and meta-analysis					Systematic review and meta-analysis			O. prospective multicenter study				O. retrospective review from a single center			Systemic review and meta-analysis			Multi institutional retrospective cohort study
N. patients (n)	686	525				415	273		202	47			52	67		632	467		169	185
Follow-up (mo)	6-12	6-12				7-12	7-16		12	12			12	12		15.5	15.8		12	12
GERD-HRQL score	POR = 0.48				0.101	20.5 vs 3	19.7 vs 3.2	NS	20 vs 3	23 vs 3.5	0.177		4.3 p.	5.1 p.	0.47	WMD = 0.34		0.525	21 vs 3	19 vs 4	0.17
PPI suspension	POR = 0.81				0.548	81.4%1	81.5%1	0.68	81.8%	63.0%	0.009		85%	92%	0.37	POR = 1.08		0.877	76%	88%	0.02
Gas/bloating	POR = 0.39				< 0.001	26.7%1	53.4%1	0.06	10.0%	31.9%	< 0.001		23%	53%	< 0.01	POR = 0.34		0.004	47%	59%	0.008
Ability to vomit	POR = 10.1				< 0.001	93.5%1	49.5%1	< 0.0001	91.3%	44.4%	< 0.001		4%	19%	< 0.01				95%	43%	< 0.001
Ability to belch	POR = 5.53				< 0.001	95.2%1	65.9%1	< 0.00001	98.4%	88.9%	0.007		10.0%	36%	< 0.01	POR = 12.34		< 0.001	96.5%	69.2%	< 0.001
Dysphagia	POR = 1.56				0.119	33.9%1	47.1%1	0.43	7%	10.6%	0.373		46%	56%	0.25	POR = 0.94		0.822	58%	47%	0.31
Operative time (min)	42-73		76-118			63.7	76.8						66	82	< 0.01				60	76	< 0.001

¹Weighted mean percent values. MSA: Magnetic sphincter augmentation; FUNDO: Fundoplication; O.: Observational; WMD: Weighted mean difference; POR: Pooled odds ratio; NS: Not statistically significant; vs: Signifies preoperative versus postoperative score; p.: Postoperative.