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Copyright ©The Author(s) 2021.
World J Gastroenterol. Dec 28, 2021; 27(48): 8227-8241
Published online Dec 28, 2021. doi: 10.3748/wjg.v27.i48.8227
Table 1 Esophageal pH measurements (mean ± SD) off proton pump inhibitors[12]
Measure Baseline
6-12 yr
P value
n = 124
n = 91
Total time (%)
pH < 49.7 (6.4)4.2 (4.9)< 0.001
Upright9.7 (7.8)4.6 (4.9)< 0.001
Supine8.3 (9.6)3.3 (7.4)< 0.001
Reflux episodes
Total number92.2 (92.2)71.5 (67.7)0.125
Number lasting > 5 min6.1 (6.0)4.3 (5.8)0.036
Longest (min)32.9 (34.2)19.6 (31.5)0.005
DeMeester score40.7 (26.5)16.3 (18.8)< 0.001