Recombinant protein Schistosoma japonicum-derived molecule attenuates dextran sulfate sodium-induced colitis by inhibiting miRNA-217-5p to alleviate apoptosis

Figure 1 rSj16 protects against acute dextran sulfate sodium-induced colitis. A: Daily changes in body weight [dextran sulfate sodium (DSS) + rSj16 vs DSS + PBS]; B: Changes in DAI (DSS + rSj16 vs DSS + PBS); C and D: Colon lengths were measured and recorded; E: Macroscopic appearance of the colons; F: The histopathological changes in the colons were examined by H&E staining (20×); G: Histopathological scores of the colons were determined. DSS: Dextran Sulfate Sodium Salt. Statistical analysis was performed using one-way ANOVA. Data are presented as means ± SD; ^aP < 0.05, ^bP < 0.01, ^cP < 0.001.