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©The Author(s) 2021.
World J Gastroenterol. Nov 28, 2021; 27(44): 7669-7686
Published online Nov 28, 2021. doi: 10.3748/wjg.v27.i44.7669
Published online Nov 28, 2021. doi: 10.3748/wjg.v27.i44.7669
Figure 10 Theoretical binding mode of calycosin and high mobility group box 1 A-box.
A: The 3D structure of high mobility group box 1 (HMGB1) A-box; B: The 3D structure of calycosin (Cal); C: 3D docking mode between Cal and HMGB1 A-box simulated by Discovery Studio and the amino acid of the active site; D: Two-dimensional schematic interaction diagram between Cal and HMGB1 A-box, the color of the amino acid residue is drawn by interaction. HMGB1: High mobility group box 1; Cal: Calycosin.
- Citation: Zhu CJ, Yang WG, Li DJ, Song YD, Chen SY, Wang QF, Liu YN, Zhang Y, Cheng B, Wu ZW, Cui ZC. Calycosin attenuates severe acute pancreatitis-associated acute lung injury by curtailing high mobility group box 1 - induced inflammation. World J Gastroenterol 2021; 27(44): 7669-7686
- URL: https://www.wjgnet.com/1007-9327/full/v27/i44/7669.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i44.7669