Gut microbiome composition can predict the response to nivolumab in advanced hepatocellular carcinoma patients

Figure 2 Composition of the gut microbiome in hepatocellular carcinoma patients is associated with the response to nivolumab. A: Heatmap showing the abundance of operational taxonomic units in responders (yellow) and non-responders (blue). The original comprehensive figure, including the names of bacterial taxa, is presented as Supplemental Figure 1; B: Unweighted beta diversity analysis showed that the overall bacterial community structure and phylogenetic diversity at T0 (light yellow and light blue) and T1 (yellow and blue) were similar; distinct clusters were not observed for responders (yellow) and non-responders (blue). Statistical values obtained by the PERMANOVA test are presented in Supplemental Table 2.