Long-term clinical outcomes of lipiodol marking using standard gastroscopy for image-guided radiotherapy of upper gastrointestinal cancers

Table 2 Patient demographics and treatment details based on fiducial-based image-guided radiotherapy and standard image-guided radiotherapy

Variables		F-IGRT	S-IGRT
		Median/n, range/%	Median/n, range/%
	Age	77.4, 57.5-88.0	77.3, 64.8-85.4
	Male	19, 70.4	1, 25.0
Site of cancer	Oesophageal	18, 62.1	3, 75.0
	GOJ (Siewert I/II)	0, 0.0	1, 25.0
	GOJ (Siewert III)	2, 7.4	0, 0.0
	Gastric	7, 25.9	0, 0.0
Type of cancer	Oesophageal SCC	13, 48.1	3, 75.0
	Oesophageal adenocarcinoma	5, 18.5	1, 25.0
	Gastric adenocarcinoma	9, 33.3	0, 0.0
Endoscopy data	Patients with both proximal and distal fiducial placed	22, 81.5	2, 50.0
	Patients with solely proximal or distal fiducials placed	5, 18.5	2, 50.0
ECOG	0	11, 40.7	2, 50.0
	1	9, 33.3	2, 50.0
	2	7, 25.9	0, 0.0
Stages1	LN negative without distant metastasis	18, 66.7	4, 100.0
	LN positive without distant metastasis	6, 22.2	0, 0.0
	Distant metastasis present	3, 11.1	0, 0.0
Treatment details	Time to treatment (d)	19.0, 9.0-44	14 .0, 9.0-17.0
	Curative intent	20, 74.1	4, 100.0
	Palliative intent	7, 25.9	0, 0.0
	Dose (Grays)	50, 25.2-55	47.7, 41.4-54
	Fraction	25, 10-30	26.5, 23-30
	Duration (d)	30, 14-47	37, 30-39
	Chemotherapy	14, 51.9	4, 100.0

¹Staging as per American Joint Committee on Cancer 8^th edition. T-stage was not available for all patients as endoscopic ultrasound is not routinely performed at our center.

F-IGRT: Fiducial-based image-guided radiotherapy; S-IGRT: Standard image-guided radiotherapy; SCC: Squamous cell carcinoma; ECOG: Eastern Cooperative Oncology Group; GOJ: Gastro-oesophageal junction; LN: Lymph Node.