Copyright
©The Author(s) 2021.
World J Gastroenterol. Nov 7, 2021; 27(41): 7190-7206
Published online Nov 7, 2021. doi: 10.3748/wjg.v27.i41.7190
Published online Nov 7, 2021. doi: 10.3748/wjg.v27.i41.7190
Table 1 Clinical characteristics of all patients in the programmed cell death-1/programmed death-ligand 1 and cytotoxic T-lymphocyte antigen 4 groups
Characteristic | PD-1/PD-L1, n = 605 | CTLA-4, n = 56 | P value |
Age, yr, median (range) | 69 (22-87) | 65 (21-85) | 0.039 |
Sex, n (%) | 0.228 | ||
Male | 419 (69.3) | 34 (60.7) | |
Female | 186 (30.7) | 22 (39.3) | |
BMI, kg/m2 | 21.3 (12.0-37.0) | 21.6 (13.9-43.0) | 0.532 |
ECOG PS, n (%) | 0.073 | ||
0-1 | 534 (88.3) | 54 (96.4) | |
2-3 | 71 (11.7) | 2 (3.6) | |
Cancer type, n (%) | |||
NSCLC | 241 (39.8) | 0 (0.0) | |
MM | 110 (18.2) | 39 (69.6) | |
RCC | 52 (8.6) | 17 (30.4) | |
GC | 49 (8.1) | 0 (0.0) | |
Others | 153(25.3) | 0 (0.0) | |
Drugs, n (%) | |||
Nivolumab | 317 (52.4) | 0 (0.0) | |
Pembrolizumab | 180 (29.8) | 0 (0.0) | |
Atezolizumab | 74 (12.2) | 0 (0.0) | |
Durvalumab | 32 (5.3) | 0 (0.0) | |
Avelumab | 2 (0.3) | 0 (0.0) | |
Ipilimumab | 0 (0.0) | 28 (50.0) | |
Nivolumab + ipilimumab | 0 (0.0) | 28 (50.0) |
- Citation: Yamada K, Sawada T, Nakamura M, Yamamura T, Maeda K, Ishikawa E, Iida T, Mizutani Y, Kakushima N, Ishikawa T, Furukawa K, Ohno E, Honda T, Kawashima H, Ishigami M, Furune S, Hase T, Yokota K, Maeda O, Hashimoto N, Akiyama M, Ando Y, Fujishiro M. Clinical characteristics of gastrointestinal immune-related adverse events of immune checkpoint inhibitors and their association with survival. World J Gastroenterol 2021; 27(41): 7190-7206
- URL: https://www.wjgnet.com/1007-9327/full/v27/i41/7190.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i41.7190