Retrospective Cohort Study
Copyright ©The Author(s) 2021.
World J Gastroenterol. Nov 7, 2021; 27(41): 7159-7172
Published online Nov 7, 2021. doi: 10.3748/wjg.v27.i41.7159
Table 5 Univariate and multivariate regression analyses of risk factors associated with surgical recurrence in propensity-score matched patients

Univariate analysis
Multivariate analysis
No recurrence (n = 183)
Recurrence (n = 21)
P
HR
95%CI
P
Demographics
Male134 (73.2)16 (76.2)1.000
Family history8 (4.4)0 (0.0)1.000
Smoking history38 (20.8)3 (14.3)0.579
Comorbidity6 (3.3)0 (0.0)1.000
Fistula-in-ano81 (44.3)9 (42.9)1.000
Previous abdominal surgery 15 (8.2)3 (14.3)0.407
Penetrating type129 (70.5)17 (81.0)0.445
Open approach95 (48.1)14 (66.7)0.166
Preoperative medications
Biologics26 (14.2)7 (33.3)0.0242.640.89-7.860.081
Steroid31 (16.9)6 (28.6)0.229
Immunomodulators88 (48.1)10 (47.6)1.000
Operation details
Indication
Fistula69 (37.7)4 (19.0)0.099
Obstruction62 (33.9)6 (28.6)0.808
Anastomosis configuration
Side-to-side150 (82.0)13 (61.9)0.0423.821.24-11.780.078
End-to-side30 (16.4)5 (23.8)0.370
Stapled anastomosis180 (98.4)21 (100.0)1.000
Additional procedures55 (30.1)11 (52.4)0.0493.281.20-8.910.020
Operation time > 135 min66 (36.1)11 (52.4)0.159