Gut microbiota in a population highly affected by obesity and type 2 diabetes and susceptibility to COVID-19

Table 2 High abundance bacterial taxa characterizing the gut microbiota dysbiosis of selected diseases

Population	Disease	Relevant taxa	Analysis	Ref.
Mexico	ED	f_Veillonellaceae, f_ S24-7, g_Ruminococcus, g_Bacteroides, g_Parvimonas, g_Oscillospira.	MaAsLin	Nirmalkar et al[87], 2018
	T2DM	o_Bacteroidales, f_Koribacteraceae, g_Suterella, g_Roseburia, g_Pelomonas, g_Oscillospira.	LEfSe	Chávez-Carbajal et al[85], 2020
	OB	f_ S24-7, g_Roseburia, g_Succinivibrio.	LEfSe	Chávez-Carbajal et al[86], 2019
		g_Lachnospira, g_Roseburia, g_Faecalibacterium.	UPGMA	Murugesan et al[88], 2015
	MetS	g_Lachnospira, g_Coprococus, g_Faecalibacterium, g_Ruminococcus, g_Megamonas.	LEfSe	Chávez-Carbajal et al[86], 2019
United States	HBP	g_Dorea, s_Alistipes finegoldii, s_A. indistinctus.	LEfSe	Kim et al[89], 2020
	ED	g_Bifidobacterium, g_Akkermansia, g_Oxalobacter.	Pearson’s correlation	Johnson et al[90], 2019
		o_Bacteroidales, f_ Prevotellaceae, g_ Hungatella, g_Succiniclasticum.	Mann Whitney U	Kummen et al[91], 2018
	T2DM	g_Bifidobacterium, g_Prevotella.	Mann-Whitney nonparametric test	Barengolts et al[92], 2018
	OB	c_Bacilli, f_Streptococcaceae, f_Lactobacillaceae, g_Streptococcus, g_Blautia.	Kruskal-Wallis	Peters et al[93], 2018
		f_Ruminococcacea, g_Prevotella, g_Gardnerella, g_Turicibacter, g_Megasphera.	LEfSe	Sergeev et al[94], 2020
	MetS	g_Ruminococcus, g_Haemophilus, g_Varibaculum, g_Veillonella, g_Sarcina, g_Lactobacillus, g_Turicibacter, g_Actinomyces, g_Bifidobacterium, g_Lachnobacterium.	Correlations	Tricò et al[95], 2019
		g_Clostridium, g_Ruminococcus, g_Faecalibacterium, g_Oscillospira, g_Coprococcus, g_Prevotella.	Compute core microbiome (95%)	Zupancic et al[96], 2012
Brazil	ED	f_Lachnospiraceae g_Roseburia g_Coprococcus	Mann–Whitney U	Silveira-Nunes et al[97], 2020
	T2DM	g_Gemella g_Coprococcus g_Desulfovibrio	Relative Abundance	Al Assal et al[98], 2020
	OB	g_Fusobacterium g_Enterococcus s_Escherichia coli	FISH	Sarmiento et al[99], 2019
	MetS	p_Firmicutes	RT-qPCR	Miranda et al[100], 2019

ED: Endothelial dysfunction; T2DM: Type 2 diabetes; OB: Obesity; MetS: Metabolic syndrome; UPGMA: Unweighted pair group method with arithmetic mean; FISH: Fluorescence in situ hybridization.