Endoscopic anti-reflux therapy for gastroesophageal reflux disease

Table 1 Comparison of current endoscopic therapies for gastroesophageal reflux disease

	TIF	MUSE	Stretta®	GERDx™	ARMS/ARMA	Band ligation
Efficacy	++	+	+ -	+	+	+
Safety	+	+	++	+	+	+
Technical difficulty	++	++	+	++	+	+
Add-on device	+	+	+	+	-	-
RCT available	+	-	+	-	-	-
Maximum follow-up (yr)	10	5	10	0.25	3	1
Cost	++	++	++	++	+	+

++: Indicates the highest score; +: Indicates a moderate score or yes; -: Indicates uncertainty; TIF: Transoral incisionless fundoplication; MUSE: Medigus ultrasonic surgical endostapler; GERDx™: Endoscopic full-thickness plication device; ARMS: Anti-reflux mucosectomy; ARMA: Anti-reflux mucosal ablation; RCT: Randomized controlled trial.