Faecal immunochemical test outside colorectal cancer screening?

Table 2 Colorectal cancer risk in patients with high risk adenomas or low risk adenomas

Ref.	Patients	Follow-up in yr	Comparison group	High risk lesions	Low risk lesions
Løberg et al[53], 2014	40826	7.7	General population	SIR 1.62 (95%CI: 1.50-1.75)	SIR 0.98 (95%CI: 0.89-1.08)
Click et al[56], 2018	15935	12.9	No adenoma group	RR 2.7 (95%CI: 1.9-3.7)	RR 1.2 (95%CI: 0.8-1.7)
Lee et al[54], 2020	64422	8.1	No adenoma group	HR 2.61 (95%CI: 1.87-3.63)	HR 1.29 (95%CI: 0.89-1.88)
Wieszczy et al[55], 2020	236089	7.1	General population	SIR 0.65 (95%CI: 0.51-0.82)	SIR 0.35 (95%CI: 0.26-0.45)
He et al[58], 2020	122899	10	No adenoma group	HR 4.07 (95%CI: 2.89-5.72)	HR 1.21 (95%CI: 0.68-2.16)
Cross et al[57], 2021	21318	10.1	General population	SIR 1.30 (95%CI: 1.03-1.62)	SIR 0.75 (95%CI: 0.63- 0.88)

HR: Hazard ratio; RR: Rate ratio; SIR: Standardized incidence ratio.