Determination of gluten immunogenic peptides for the management of the treatment adherence of celiac disease: A systematic review

doi:10.3748/wjg.v27.i37.6306

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Oct 7, 2021 (publication date) through Dec 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 7, 2021; 27(37): 6306-6321
Published online Oct 7, 2021. doi: 10.3748/wjg.v27.i37.6306

Table 2 Available immunomethods to detect gluten immunogenic peptides in stool and urine

Technique	Antibodies	Sample	Analytical sensitivity	Diagnostic sensitivity	Diagnostic specificity	Ref.
ELISA	G12/G12	Stool	0.16 µg/g	0.98	1	[8]
LFIA	G12/A1	Stool	0.15 µg/g	0.97	1	[56]
LFIA	G12/A1	Urine	2.2 ng/mL (LOD), 6.25 ng/mL (LOQ)	0.91	0.99	[9]

ELISA: Enzyme-like immunosorbent assay; LFIA: Lateral flow immunoassay; LOD: Limit of detection; LOQ: Limit of quantification.

Citation: Coto L, Mendia I, Sousa C, Bai JC, Cebolla A. Determination of gluten immunogenic peptides for the management of the treatment adherence of celiac disease: A systematic review. World J Gastroenterol 2021; 27(37): 6306-6321
URL: https://www.wjgnet.com/1007-9327/full/v27/i37/6306.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i37.6306