CircRNA_0084927 promotes colorectal cancer progression by regulating miRNA-20b-3p/glutathione S-transferase mu 5 axis

Figure 6 AKT-mTOR pathway is inactivated by circRNA_0084927 knockdown and rescued by miRNA-20b-3p. A: Expression of AKT-mTOR pathway molecules after transfecting miRNA-20b-3p (miR-20b-3p) mimic; B: Expression of AKT-mTOR pathway molecules after transfecting circRNA_0084927 (circ_0084927); C: Expression of AKT-mTOR pathway molecules after transfecting sh-circ_0084927 plasmid and miR-20b-3p inhibitor. Data are presented as the mean ± SEM. ^aP < 0.05; ^bP < 0.01. Sh-circ_0084927: Short hairpin circ_0084927 plasmid; Sh-NC: Short hairpin negative control plasmid; NC mimic: Negative control mimic.