CircRNA_0084927 promotes colorectal cancer progression by regulating miRNA-20b-3p/glutathione S-transferase mu 5 axis

Figure 4 The function of circRNA_0084927 in HCT116 cells with circRNA_0084927 knockdown is rescued by miRNA-20b-3p. A: Expression of miRNA-20b-3p (miR-20b-3p); B: Viability of HCT116 cells detected after transfecting circRNA_0084927 (circ_0084927) or miR-20b-3p inhibitor; C-G: Migration and invasion of HCT116 cells tested by wound healing assay (C and D) and transwell assay (E-G) after transfecting sh-circ_0084927 plasmid or miR-20b-3p inhibitor. Data are presented as the mean ± SEM. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001. Sh-circ_0084927: Short hairpin circ_0084927 plasmid; Sh-NC: Short hairpin negative control plasmid; miR-20b-3p: miRNA-20b-3p.