Impact of radiogenomics in esophageal cancer on clinical outcomes: A pilot study

Table 3 Selected radiomic features after the three feature selection steps for body mass index

Selected radiomic features	mean ± SD	ρ	P value
Wavelet-HLH GLCM IMC2	0.46 ± 0.31	0.6	0.017
Wavelet-HLH GLCM MCC	0.33 ± 0.27	0.67	0.006
Wavelet-HLH first order median	0.59 ± 0.28	-0.56	0.029
Wavelet-HLH first order entropy	0.32 ± 0.33	0.63	0.013
Wavelet-HLH first order root mean squared	0.44 ± 0.31	0.71	0.003
Wavelet-HLH first order skewness	0.5 ± 0.33	0.52	0.049
Wavelet-HLH first order mean absolute deviation	0.54 ± 0.29	0.62	0.013
Wavelet-LHL GLCM IDN	0.77 ± 0.29	0.58	0.023
Wavelet-LHL GLDM high gray level emphasis	0.31 ± 0.29	0.54	0.039
Wavelet-HLL GLRLM high gray level run emphasis	0.32 ± 0.32	0.54	0.038
Wavelet-HLL GLRLM gray level variance	0.36 ± 0.37	0.62	0.014
Wavelet-HLL GLCM cluster prominence	0.26 ± 0.36	0.6	0.018
Wavelet-HLL GLCM inverse variance	0.57 ± 0.3	-0.58	0.022
Wavelet-HLL GLCM maximum probability	0.47 ± 0.35	-0.53	0.043
Wavelet-HLL GLDM dependence variance	0.41 ± 0.27	-0.6	0.018
Wavelet-HLL GLSZM size zone non uniformity	0.29 ± 0.33	0.57	0.028
Wavelet-HHH GLRLM gray level non uniformity normalized	0.74 ± 0.3	-0.54	0.039
Wavelet-HHH GLCM difference average	0.64 ± 0.31	0.56	0.03
Wavelet-HHH GLCM contrast	0.53 ± 0.28	0.64	0.009
Wavelet-HHH GLSZM small area emphasis	0.55 ± 0.33	0.69	0.005
Wavelet-HHH GLSZM small area low gray level emphasis	0.55 ± 0.33	0.59	0.022
Wavelet-HHL first order entropy	0.38 ± 0.3	0.57	0.025
Wavelet-HHL first order mean	0.64 ± 0.28	0.59	0.02
Wavelet-HHL first order mean absolute deviation	0.36 ± 0.29	0.55	0.032
Wavelet-LLH NGTDM complexity	0.16 ± 0.26	0.53	0.044
Wavelet-LLL GLDM small dependence high gray level emphasis	0.36 ± 0.3	0.56	0.031
Log-sigma-1-0-mm-3D first order root mean squared	0.43 ± 0.26	-0.51	0.049
Log-sigma-5-0-mm-3D GLRLM short run low gray level emphasis	0.22 ± 0.25	-0.52	0.047
Log-sigma-5-0-mm-3D first order 10 percentile	0.48 ± 0.39	-0.59	0.02

GLCM: Gray level co-occurrence matrix; GLDM: Gray level dependence matrix; GLRLM: Gray level run length matrix; GLSZM: Gray level size zone matrix; H: High-pass filter; L: Low-pass filter; NGTDM: Neighboring gray tone difference matrix; SD: Standard deviation.