Characterization of gut microbiome and metabolome in Helicobacter pylori patients in an underprivileged community in the United States

Figure 1 Chao1 index alpha diversity and observed operational taxonomic units by Helicobacter pylori status stratified by age. A: Chao1 index alpha diversity is compared between Helicobacter pylori (H. pylori) patients (blue) and control subjects (orange), subgrouped by age. H. pylori patients over 40 years old (n = 16) had significantly lower Chao1 scores compared to control subjects over 40 (n = 4) (Kruskal-Wallis H = 6.036, P = 0.014). Boxes represent 1^st and 3^rd quartiles, and central lines represent median values. Whiskers represent non-outlier high and low values. Points show outliers, which were determined by having a distance from the 1^st or 3^rd quartile greater than 1.5 times the interquartile range; B: Observed operational taxonomic units (operational taxonomic units) are compared between H. pylori patients (blue, n = 19) and control subjects (orange, n = 16), as a function of age. Shading around the regression lines indicates 95% confidence intervals. OTU: Operational taxonomic units; H. pylori: Helicobacter pylori.