Radiomics for predicting perineural invasion status in rectal cancer

Table 4 Subgroup analyses of the models in the whole cohort

	The clinical model			The combined model			P value
Subgroups	AUC	SEN (%)	SPE (%)	AUC	SEN (%)	SPE (%)
nCRT
With (n = 62)	0.710 (0.581-0.818)	68.00	75.68	0.853 (0.740-0.930)	68.00	89.19	0.011
Without (n = 241)	0.712 (0.650-0.768)	48.74	83.61	0.814 (0.759-0.861)	65.55	87.70	< 0.001
Stage
II (n = 62)	0.553 (0.422-0.680)	21.05	93.02	0.670 (0.538-0.784)	36.84	100.00	0.098
III (n = 193)	0.630 (0.558-0.698)	56.52	69.23	0.796 (0.732-0.851)	73.04	79.49	< 0.001

P value: Comparisons between the clinical model and combined model. AUC: Area under the receiver operating characteristic curve; SEN: Sensitivity; SPE: Specificity; nCRT: Neoadjuvant chemoradiotherapy.