Recombinant angiopoietin-like protein 4 attenuates intestinal barrier structure and function injury after ischemia/reperfusion

Figure 3 Recombinant human angiopoietin-like protein 4 regulates the intestinal permeability barrier and myosin light chain kinase-tight junction pathway related proteins in vivo. Intestinal mucosal tissue myosin light chain kinase (MLCK), phosphorylated-myosin light chain (p-MLC)/myosin light chain, zonula occludens-1 (ZO-1) and claudin-2 (CLDN-2) (A) and intestinal mucosal permeability (B) in different groups (mean ± SD, n = 8). ^bP < 0.01 vs sham; ^dP < 0.01 vs ischemia-reperfusion (I/R). ANGPTL4: Angiopoietin-like protein 4; t-MLC: Total-myosin light chain.