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©The Author(s) 2021.
World J Gastroenterol. Aug 28, 2021; 27(32): 5306-5321
Published online Aug 28, 2021. doi: 10.3748/wjg.v27.i32.5306
Published online Aug 28, 2021. doi: 10.3748/wjg.v27.i32.5306
Table 3 Key characteristics of the main studies using radiomics and machine learning algorithms on magnetic resonance images to predict outcome other than pathologic complete response after neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer
Ref. | Study design (n of sites) | Number of patients | Prediction task | CT phase (n of CT scanner) | Segmentation method | ML algorithm | Data powering algorithm | Validation | Performance |
Bibault et al[85], 2018 | Retrospective (3) | 99 | pCR after nCRT | Unenhanced (3) | Manual – 3D | DNN | Radiomics and clinical features | Internal validation (cross-validation) | AUC: 0.72 |
Hamerla et al[86], 2019 | Retrospective (1) | 169 | pCR after nCRT | Unenhanced (1) | Manual – 3D | RF | Radiomics features | Internal validation (cross-validation) | Accuracy: 0.87 |
Yuan et al[87], 2020 | Retrospective (1) | 91 | pCR after nCRT | Unenhanced (1) | Manual – 3D | RF | Radiomics features | Internal validation (train/validation split) | Accuracy: 0.84 |
Wu et al[90], 2019 | Retrospective (1) | 102 | MSI status | Venous phase - DECT (2) | Manual - 3 2D ROIs for lesion | LR | Radiomics features | Internal validation (train/validation /test split) | AUC: 0.87 |
Fan et al[91], 2019 | Retrospective (1) | 100 | MSI status | Portal venous phase (2) | Semiautomatic – 3D | NB | Radiomics features | Internal validation (cross-validation) | AUC: 0.75 |
Wu et al[92], 2020 | Retrospective (1) | 173 | KRAS mutation | Portal venous phase (3) | Manual + DL – single 2D ROI | LR | Radiomics features | Internal validation (train/test split) | C-index: 0.83 |
Wang et al[94], 2019 | Retrospective (1) | 411 | Prediction of survival | Unenhanced (1) | Manual – 3D | 10-F CV | Radiomics and clinical features | Internal validation (cross-validation) | C-index: 0.73 |
- Citation: Stanzione A, Verde F, Romeo V, Boccadifuoco F, Mainenti PP, Maurea S. Radiomics and machine learning applications in rectal cancer: Current update and future perspectives. World J Gastroenterol 2021; 27(32): 5306-5321
- URL: https://www.wjgnet.com/1007-9327/full/v27/i32/5306.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i32.5306