Histological differentiation impacts the tumor immune microenvironment in gastric carcinoma: Relation to the immune cycle

Figure 3 Relationship between programmed death-ligand 1 expression, gastric carcinoma immunophenotype and number of M1 and M2 macrophages. A: Frequency of programmed death-ligand 1 (PD-L1) expression in gastric carcinoma (GC) of different tumor immune microenvironment (TIME); B: PD-L1 expression in tumor cells of Inflamed TIME GC, immunohistochemistry for PD-L1, × 50; C and D: number of M1 (C) and M2 (D)-macrophages in GC regarding PD-L1 expression. PD-L1: Programmed death-ligand 1; CPS: Combined positive score.