Prediction of the severity of colorectal lesion by fecal hemoglobin concentration observed during previous test in the French screening program

doi:10.3748/wjg.v27.i31.5272

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 21, 2021; 27(31): 5272-5287
Published online Aug 21, 2021. doi: 10.3748/wjg.v27.i31.5272

Table 4 Number of colorectal lesions and the proportion of colorectal cancer among colorectal lesions by localization, according to the previous rate and the last rate of fecal hemoglobin

Fhb₍₀₎ by Fhb_(-1)		Colorectal lesion number (%Specified localization)	Number of colorectal lesions by localization and proportion of CRC
Fhb₍₀₎ by Fhb_(-1)		Colorectal lesion number (%Specified localization)	Specified localization: number (% CRC)	Cecum: number (% CRC)	Right colon: number (% CRC)	Transverse colon: number (%CRC)	Left colon: number (%CRC)	Rectosigmoid: number (%CRC)	P value¹
Fhb_(-1) (ngHb/mL)	Fhb₍₀₎ (ngHb/mL)
Overall	150-300	4390 (57.0)	2500 (5.4)	195 (6.7)	490 (5.3)	221 (3.2)	252 (3.2)	1342 (6.1)	0.2
	> 300	4358 (59.7)	2600 (13.4)	179 (16.8)	432 (11.8)	176 (11.4)	235 (11.1)	1578 (14.1)	0.3
	Total	8748 (58.3)	5100 (9.5)	374 (11.5)	922 (8.4)	397 (6.8)	487 (7.0)	2920 (10.4)	0.01
0	150-300	3609 (55.7)	2011 (5.3)	154 (7.8)	391 (5.1)	176 (2.8)	200 (3.0)	1090 (5.8)	0.2
	> 300	3476 (58.2)	2022 (12.0)	145 (14.5)	355 (10.1)	139 (8.6)	185 (10.3)	1198 (12.9)	0.3
	Subtotal	7085 (56.9)	4033 (8.6)	299 (11.0)	746 (7.5)	315 (5.4)	385 (6.5)	2288 (9.5)	0.02
0-50	150-300	63 (61.9)	39 (10.3)	2 (0.0)	6 (16.7)	4 (0.0)	8 (12.5)	19 (10.5)	1.0
	> 300	70 (55.7)	39 (12.8)	2 (0.0)	4 (25.0)	2 (0.0)	3 (0.0)	28 (14.3)	0.8
	Subtotal	133 (58.7)	78 (11.5)	4 (0.0)	10 (20)	6 (0.0)	11 (9.1)	47 (12.8)	0.9
50-100	150-300	464 (62.1)	288 (5.6)	24 (0.0)	66 (4.6)	23 (4.4)	23 (0.0)	152 (7.9)	0.5
	> 300	519 (63.0)	327 (17.1)	22 (27.3)	46 (17.4)	21 (23.8)	29 (10.3)	209 (16.3)	0.5
	Subtotal	983 (62.6)	615 (11.7)	46 (13.0)	112 (9.8)	44 (13.6)	52 (5.8)	361 (12.7)	0.6
100-149	150-300	254 (63.8)	162 (6.2)	15 (6.7)	27 (7.4)	18 (5.6)	21 (4.8)	81 (6.2)	1.0
	> 300	293 (72.4)	212 (21.7)	10 (30.0)	27 (22.2)	14 (21.4)	18 (22.2)	143 (21.0)	1.0
	Subtotal	547 (68.4)	374 (15)	25 (16.0)	54 (14.8)	32 (12.5)	39 (12.8)	224 (15.6)	1.0

¹Pearson Chi-2 test or Fisher's exact test. CRC: Colorectal cancer; Fhb₍₀₎: Fecal hemoglobin measured at test₍₀₎(last screening test); Fhb_(-1): Fecal hemoglobin measured at test_(-1)(penultimate test).

Citation: Balamou C, Koïvogui A, Rodrigue CM, Clerc A, Piccotti C, Deloraine A, Exbrayat C. Prediction of the severity of colorectal lesion by fecal hemoglobin concentration observed during previous test in the French screening program. World J Gastroenterol 2021; 27(31): 5272-5287
URL: https://www.wjgnet.com/1007-9327/full/v27/i31/5272.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i31.5272