Prediction of the severity of colorectal lesion by fecal hemoglobin concentration observed during previous test in the French screening program

Table 3 Colonoscopy detection rate and proportion of colorectal cancer among colorectal lesions according to the previous rate of fecal hemoglobin and the age at the time of the previous test

Fhb(-1) by age at test(-1)		Colonoscopy detection rate and CRC proportion
		Number Colo (%Positive colo)	P value1	Number of lesions (%CRC)	P value2
Age (yr) at test(-1)	Fhb(-1) (ngHb/mL)
Overall		11254 (77.7)		8748 (5.7)
50-54			<10-3		0.7
	0	1471 (71.6)		1053 (3.1)
	0-50	21 (71.4)		15 (0.0)
	50-100	130 (90.8)		118 (2.5)
	100-150	68 (86.8)		59 (5.1)
	Subtotal	1690 (73.7)		1245 (3.1)
55-59			< 10-3		0.1
	0	1797 (73.7)		1324 (3.9)
	0-50	31 (67.7)		21 (4.8)
	50-100	178 (87.1)		155 (7.1)
	100-150	101 (91.1)		92 (7.6)
	Subtotal	2107 (75.6)		1592 (4.5)
60-64			< 10-3		0.05
	0	2044 (76.4)		1562 (4.6)
	0-50	37 (70.3)		26 (7.7)
	50-100	247 (90.3)		223 (8.1)
	100-150	121 (90.1)		109 (8.3)
	Subtotal	2449 (78.4)		1920 (5.3)
65-69			< 10-3		0.001
	0	2373 (76.5)		1815 (6.2)
	0-50	54 (90.7)		49 (8.2)
	50-100	308 (88)		271 (8.1)
	100-150	172 (88.4)		152 (15.8)
	Subtotal	2907 (78.7)		2287 (7.1)
≥70			< 10-3		0.01
	0	1683 (79.1)		1331 (6.5)
	0-50	29 (75.9)		22 (9.1)
	50-100	245 (88.2)		216 (10.2)
	100-150	144 (93.8)		135 (13.3)
	Subtotal	2101 (81.1)		1704 (7.6)

¹Pearson Chi-2 test.

²Fisher's exact test. CRC: Colorectal cancer; Colo: Colonoscopy; Fhb_(-1): Fecal hemoglobin measured at test_(-1) (penultimate test).