Retrospective Study
Copyright ©The Author(s) 2021.
World J Gastroenterol. Aug 21, 2021; 27(31): 5259-5271
Published online Aug 21, 2021. doi: 10.3748/wjg.v27.i31.5259
Table 2 Immune cells number in gastric carcinoma of different histological types and tumor immune microenvironment
CharacteristicsCD8+ cells
CD68+ cells
CD163+ cells
TC
TS
TC
TS
TC
TS
Histological type
Intestinal 214 ± 44.9202 ± 14.7303 ± 21.7244 ± 12.4173 ± 17.3170 ± 9.67
124-305173-232259-347219-269138-208151-190
Diffuse 49.5 ± 6.6366.0 ± 6.03339 ± 23.6225 ± 23.851.7 ± 8.6055.5 ± 8.94
36.0-63.143.6-98.3291-388176-27434.1-69.437.2-73.9
Mucinous 7.53 ± 2.5052.5 ± 37.5101 ± 59.0219 ± 16.212.5 ± 11.862.5 ± 12.5
2.26-34.323.9-82.964-125126-2646.32-78.236-121
P = 0.045P = 0.059P = 0.071P = 0.471P = 0.032P = 0.011
TIME type
ID 43.7 ± 4.0543.2 ± 5.93367.5 ± 36.9213.1 ± 35.972.5 ± 18.348.7 ± 10.5
35.1-52.330.6-55.7288-446135-29033.2-11126.2-71.2
IE19.4 ± 3.43112 ± 15.2157.3 ± 29.6266.6 ± 25.855.5 ± 13.6119.5 ± 16.3
12.2-26.780.1-14494.5-220211-32126.5-84.484.9-154.1
Inflamed 229 ± 44.9190 ± 16.5352.8 ± 15.6232.6 ± 13.7165.6 ± 18.2151.3 ± 12.1
138-319156-223321-384204-260128-202126-175
P = 0.042P = 0.004P = 0.674P = 0.060P = 0.024P = 0.011
Status PD-L1 expression
Positive341 ± 72.3204 ± 52.7430 ± 27.7200 ± 8.19231 ± 54.3135 ± 29.5
66.3-48858.4-350341-518174-22658.4-40441.3-229
Negative49.0 ± 13.1116 ± 20.7261 ± 41.4279 ± 37.996.3 ± 28.0131 ± 28.2
20.1-77.972.0-159169-352195-36234.6-15769.5-193
P = 0.010P = 0.075P = 0.252P = 0.715P = 0.032P = 0.260