Estrogen augmented visceral pain and colonic neuron modulation in a double-hit model of prenatal and adult stress

doi:10.3748/wjg.v27.i30.5060

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Aug 14, 2021 (publication date) through Feb 21, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 14, 2021; 27(30): 5060-5075
Published online Aug 14, 2021. doi: 10.3748/wjg.v27.i30.5060

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Figure 5 Brain-derived neurotrophic factor expression in lumbar-sacral spinal cord is regulated by estrogen. A: Plasma estrogen levels in cycling females that received a bolus estradiol (E2) infusion on day 1; B: Lumbar-sacral spinal cord brain-derived neurotrophic factor (BDNF) mRNA following bolus estrogen infusion; C: Lumbar-sacral spinal cord BDNF protein following bolus estrogen infusion. (n = 8 rats in each group, two-way ANOVA, ^aP < 0.05 vs vehicle group).

Citation: Chen JH, Sun Y, Ju PJ, Wei JB, Li QJ, Winston JH. Estrogen augmented visceral pain and colonic neuron modulation in a double-hit model of prenatal and adult stress. World J Gastroenterol 2021; 27(30): 5060-5075
URL: https://www.wjgnet.com/1007-9327/full/v27/i30/5060.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i30.5060