Assessing disease activity using the pediatric Crohn’s disease activity index: Can we use subjective or objective parameters alone?

Table 2 Linear regression analysis examining the contribution of pediatric Crohn’s disease activity index change scores to Q1 and Q4 pediatric Crohn’s disease activity index disease activity

	PCDAI∆ Q1 to BL (n = 670)
	Full scale	Subjective	Objective	Composite
	β values	β values	β values	β values
1. Abdominal pain	0.57b	0.80b		0.65b
2. Stooling	0.42b	0.53b		0.45b
3. Well-being	0.13
4. HCT	-0.09
5. ESR	0.94b		1.27b	0.96b
6. Albumin	0.46b		0.41b	0.45b
7. Weight	0.30b		0.52b	0.32b
8. Height Velocity	0.50b		0.56b	0.48b
9. Abdominal exam	0.08
10. Perirectal exam	0.47b		0.45a	0.48b
11. Extraintestinal	0.13
R2	0.32	0.18	0.21	0.32
	PCDAI∆ Q4 to BL (n = 474)
1. Abdominal Pain	0.45b	0.65b		0.45b
2. Stooling	0.42a	0.52b		0.42a
3. Well-being	0.58b	0.87b		0.58b
4. HCT	-0.01
5. ESR	1.32b		1.56b	1.32b
6. Albumin	0.81b		0.84b	0.81b
7. Weight	0.49b		0.63b	0.49b
8. Height velocity	0.45b		0.48b	0.45b
9. Abdominal exam	0.35a		0.83b	0.35a
10. Perirectal exam	0.78b		0.90b	0.78b
11. Extraintestinal	0.42a		0.67a	0.42b
R2	0.45	0.22	0.36	0.45

^aP < 0.05.

^bP ≤ 0.001. PCDAI: Pediatric Crohn’s disease activity index; HCT: Hematopoietic cell transplantation; ESR: Erythrocyte sedimentation rate.