Copyright
©The Author(s) 2021.
World J Gastroenterol. Jan 21, 2021; 27(3): 240-254
Published online Jan 21, 2021. doi: 10.3748/wjg.v27.i3.240
Published online Jan 21, 2021. doi: 10.3748/wjg.v27.i3.240
Figure 4 Circular RNA AKT3 knockdown suppressed growth of esophageal cancer in vivo.
A: The expression of circular RNA AKT3 (circAKT3) in TE-1 cells with circAKT3 short hairpin (sh)RNA transfection; B and C: The size (B) and weight (C) of the xenograft tumor injected with circAKT3 shRNA-transfected TE-1 cells; D-G: The expression of circAKT3 (D), miR-17-5p (E), RHOC (F) and STAT3 (G) in the xenograft tumor injected with circAKT3 shRNA-transfected TE-1 cells by quantitative real time-polymerase chain reaction; H: The protein levels of RHOC and STAT3 in the xenograft tumor injected with circAKT3 shRNA-transfected TE-1 cells. cP < 0.001. sh-NC: Negative control shRNA; sh-circAKT3: Circular RNA AKT3 shRNA.
- Citation: Zang HL, Ji FJ, Ju HY, Tian XF. Circular RNA AKT3 governs malignant behaviors of esophageal cancer cells by sponging miR-17-5p. World J Gastroenterol 2021; 27(3): 240-254
- URL: https://www.wjgnet.com/1007-9327/full/v27/i3/240.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i3.240