Copyright
©The Author(s) 2021.
World J Gastroenterol. Jul 28, 2021; 27(28): 4582-4602
Published online Jul 28, 2021. doi: 10.3748/wjg.v27.i28.4582
Published online Jul 28, 2021. doi: 10.3748/wjg.v27.i28.4582
Figure 4 Hallmarks of hypoxia in pancreatic cancer.
The figure summarizes the major adaptive features of pancreatic tumor cells in response to hypoxia. In general, low O2 availability worsens the prognosis of pancreatic cancer by promoting increases in tumor progression, drug resistance, immune evasion, and metastatic ability. Created with BioRender.com. ECM: Extracellular matrix; PSC: Pancreatic stellate cells.
- Citation: Estaras M, Gonzalez A. Modulation of cell physiology under hypoxia in pancreatic cancer. World J Gastroenterol 2021; 27(28): 4582-4602
- URL: https://www.wjgnet.com/1007-9327/full/v27/i28/4582.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i28.4582