Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket?

doi:10.3748/wjg.v27.i26.4045

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2021; 27(26): 4045-4087
Published online Jul 14, 2021. doi: 10.3748/wjg.v27.i26.4045

Table 4 Urinary biomarkers implicated in the detection of pancreatic cancer

Type	Candidate marker
Protein	LYVE1[334], REG1A[334], TTF1[334], TIMP1[335], MMP-2[335], NGAL[336], PGE2 metabolites[337], CD59 glycoprotein (CD59)[338], ANXA2[338], 21 kDA gelsolin fragment[338], S100A9[338]
Liquid biopsy	UcfDNA: KRAS mutation[341]; Exosomal miRNA: miR-3940-5p[342], miR-8069[342]
RNA	MiRNA: miR-143[340], miR-223[340], miR30e[340], miR-1246[18]
Metallomics	Calcium[344], magnesium[344]
Other	VOCs[343]

MiRNA: MicroRNA; ANXA2: Annexin A2; S200A9: Protein S100-A9.

Citation: O'Neill RS, Stoita A. Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket? World J Gastroenterol 2021; 27(26): 4045-4087
URL: https://www.wjgnet.com/1007-9327/full/v27/i26/4045.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i26.4045