Viral hepatitis update: Progress and perspectives

doi:10.3748/wjg.v27.i26.4018

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Jul 14, 2021 (publication date) through Feb 11, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2021; 27(26): 4018-4044
Published online Jul 14, 2021. doi: 10.3748/wjg.v27.i26.4018

Table 5 Hepatitis D virus highlights

	Hepatitis D virus
1	The natural course and outcome of acute hepatitis D differ according to HBV and HDV co-infection or superinfection
2	HDV and HBV genotypes in addition to host factors influence the course of chronic hepatitis
3	The implications on liver disease of HVD, HBV, and innate immunity interplay remain to be understood
4	Chronic setting leads to more severe hepatitis associated with higher rates of HCC and a faster progression to cirrhosis compared with HBV monoinfection. HDV pathologic changes are limited to the liver with histopathologic features that are not specific for it
5	HDV remains difficult to treat with the current available therapies, and although, several promising new therapies have been described treatment is still the greatest challenge in HDV infection

HDV: Hepatitis D virus; HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma.

Citation: Pisano MB, Giadans CG, Flichman DM, Ré VE, Preciado MV, Valva P. Viral hepatitis update: Progress and perspectives . World J Gastroenterol 2021; 27(26): 4018-4044
URL: https://www.wjgnet.com/1007-9327/full/v27/i26/4018.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i26.4018