Review
Copyright ©The Author(s) 2021.
World J Gastroenterol. Jul 14, 2021; 27(26): 4018-4044
Published online Jul 14, 2021. doi: 10.3748/wjg.v27.i26.4018
Table 2 Hepatitis A virus highlights

Hepatitis A virus
1The risk of HAV infection is associated with the lack of safe water and poor and sanitation
2Due to the vaccine introduction in childhood, young adults are becoming more susceptible to HAV infections
3In countries where waterborne transmission is rare, outbreaks occur among men who have sex with men, injecting drug users and contaminated food
4Since molecular detection is not routinely performed for diagnosis, surveillance programs, including viral amplification and sequencing, are needed to know the strains that circulate in a certain place
5One of the greatest challenges for HAV is to increase vaccination coverage globally, still implementing the single-dose schedule, to decrease the new infections, and, in the long term, to achieve its eradication