Copyright
©The Author(s) 2021.
World J Gastroenterol. Jul 14, 2021; 27(26): 3984-4003
Published online Jul 14, 2021. doi: 10.3748/wjg.v27.i26.3984
Published online Jul 14, 2021. doi: 10.3748/wjg.v27.i26.3984
Previous and current definition and nomenclature | |
Criteria to confirm of HRS vs other etiology of renal dysfunction | To diagnose HRS, patients must have: (1) The presence of ascites; (2) No improvement of creatinine after holding diuretics; (3) No improvement after 48 h of albumin supplementation (1 g/kg/d); (4) No signs of shock; (5) No recent nephrotoxic medications (antibiotics, contrast, NSAIDs); and (6) No signs of kidney disease (proteinuria, microhematuria, no findings on renal ultrasound) |
HRS type 1 (most recent definition in 2007) | Rapid renal injury (within two weeks) defined by 2 × baseline serum creatinine to a value > 2.5 mg/dL or 50% reduction in creatinine clearance |
HRS type 2 | Moderate renal failure with creatinine ranging from 1.5 to 2.5 mg/dL that occurs progressively |
Definition of HRS-AKI | Patients with the criteria above and ICA-AKI 2015 definition for AKI |
Definition of HRS-CKD | Patients who meet the criteria in row 1 and the rise of serum creatinine and changes in urine output are all progressive (> 1 wk) |
Patients with HRS-CKD are known to have decreased urine output over weeks to months |
- Citation: Gupta K, Bhurwal A, Law C, Ventre S, Minacapelli CD, Kabaria S, Li Y, Tait C, Catalano C, Rustgi VK. Acute kidney injury and hepatorenal syndrome in cirrhosis. World J Gastroenterol 2021; 27(26): 3984-4003
- URL: https://www.wjgnet.com/1007-9327/full/v27/i26/3984.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i26.3984