Zinc oxide nanoparticles reduce the chemoresistance of gastric cancer by inhibiting autophagy

Figure 1 Zinc oxide nanoparticle inhibits proliferation and induces apoptosis of gastric cancer cells. SGC7901 and BGC823 cells were treated with the zinc oxide nanoparticle (ZnO-NP, 5 μg/mL) or an equal volume of saline. A and B: Cell viability was analyzed by the MTT assay; C and D: Cell proliferation was assessed by the colony formation assay; E and F: Cell apoptosis was measured by flow cytometry. Data are presented as the mean ± SD. Statistically significant differences are indicated: ^aP < 0.05; ^bP < 0.01. FITC: Fluorescein isothiocyanate.