Clinical characteristics of patients in their forties who underwent surgical resection for colorectal cancer in Korea

Table 1 Patient characteristics

	30s (n = 120)	40s (n = 451)	50s (n = 1044)	P value1	P value2	P value3	P value4
Sex, male (%)	55.0	56.8	65.7	0.730	0.001	0.020	0.001
Co-morbidity (%)	28.3	37.3	52.9	0.070	< 0.001	< 0.001	< 0.001
Endocrine	3.3	9.5	14.3	0.028	0.012	0.001	< 0.001
CVD	2.5	11.8	29.8	0.002	< 0.001	< 0.001	< 0.001
Pulmonary	5.8	3.5	6.3	0.259	0.031	0.835	0.096
Other	20.8	21.1	20.6	0.956	0.837	0.951	0.979
ASA score (%)				0.079	< 0.001	< 0.001	< 0.001
1	47.5	40.8	30.4
2	50.8	56.3	66.3
3	0	2.0	2.4
4	0	0.2	0.1
5	0	0	0.1
Unknown	0.8	0.7	0.8
BMI, mean (kg/m2)	23.2	23.3	23.7	0.899	0.023	0.143	0.049
Tumor location (%)				0.975	0.061	0.268	0.126
Right-sided colon	20.0	16.0	20.9
Left-sided colon	21.7	29.0	27.7
Rectum	55.8	53.4	50.0
Multiple	2.5	1.6	1.5
CEA, median (ng/mL)	1.8	2.5	2.1	0.497	0.615	0.190	0.462
CA, median 19-9 (IU/mL)	11.1	12.6	11.3	0.215	0.527	0.887	0.781
Neoadjuvant treatment (%)	26.7	25.5	15.3	0.795	< 0.001	0.002	< 0.001
Preoperative complication (%)	14.2	17.3	12.9	0.678	0.910	0.637	0.883
Treatment	3.3	7.8	5.8	0.378	0.327	0.706	0.517

¹30s vs 40s.

²40s vs 50s.

³30s vs 50s.

⁴30s vs 40s vs 50s. CVD: Cardiovascular disease; ASA: American Society of Anesthesiologists; BMI: Body mass index; CEA: Carcinoembryonic antigen.