Diverse expression patterns of mucin 2 in colorectal cancer indicates its mechanism related to the intestinal mucosal barrier

doi:10.3748/wjg.v27.i25.3888

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Jul 7, 2021 (publication date) through Jan 25, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2021; 27(25): 3888-3900
Published online Jul 7, 2021. doi: 10.3748/wjg.v27.i25.3888

Table 3 Comparison of serum levels of diamine oxide, D-lactate, and mucin 2 between colorectal cancer patients and normal control (mean ± SD)

Group	n (%)	DAO (pg/mL)	D-LAC (μg/L)	MUC2 (ng/L)
Normal control	20	158.21 ± 15.98	973.69 ± 128.08	305.98 ± 31.50
CRC	66	185.40 ± 25.49	1216.93 ± 204.20	364.58 ± 48.30
P value		< 0.01	< 0.01	< 0.01

There were 66 cases of colorectal cancer (CRC) and 20 cases of normal controls. Serum levels of mucin 2, diamine oxide, D-lactate in CRC patients were higher than those in the normal control group. MUC2: Mucin 2; DAO: Diamine oxide; D-LAC: D-lactate; CRC: Colorectal cancer.

Citation: Gan GL, Wu HT, Chen WJ, Li CL, Ye QQ, Zheng YF, Liu J. Diverse expression patterns of mucin 2 in colorectal cancer indicates its mechanism related to the intestinal mucosal barrier. World J Gastroenterol 2021; 27(25): 3888-3900
URL: https://www.wjgnet.com/1007-9327/full/v27/i25/3888.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i25.3888