Altered profiles of fecal bile acids correlate with gut microbiota and inflammatory responses in patients with ulcerative colitis

Figure 1 Structural characteristics of intestinal microbes in the ulcerative colitis and control groups. A: Among the 594 operational taxonomic units (OTUs) detected, a total of 317 OTUs were identified in the two groups, including 86 unique OTUs in the UC group and 191 unique OTUs in the control group. B: The dilution curve analysis based on the Chao1 index for community richness and the Shannon index for community diversity showed that the sequencing volume had covered all the microorganisms in the samples. C: The species accumulation curve shows that the sequencing sample size was sufficient, which reflected most of the microbial information in the sample. D: Principal coordinate analysis clearly differentiated the intestinal flora of the ulcerative colitis (UC) group from the control group. E: Chao community richness index or the Shannon and Simpson community α diversity indexes of the UC group were significantly lower than those of the control group. F: The community compositions of the intestinal microbes in the UC group and the control group were analyzed at the phylum and genus levels. UC: Ulcerative colitis; OTUs: Operational taxonomic units; PCoA: Principal coordinate analysis.