Copyright
©The Author(s) 2021.
World J Gastroenterol. Jun 14, 2021; 27(22): 2994-3009
Published online Jun 14, 2021. doi: 10.3748/wjg.v27.i22.2994
Published online Jun 14, 2021. doi: 10.3748/wjg.v27.i22.2994
Table 1 Regulatory T cell function and recruitment in hepatocellular carcinoma
Treg function in HCC | Ref. | |
Molecule | Target | |
IL-10 | IL-10R | Marra and Tacke[90] |
IL-35 | IL-12Rβ2 | Shen et al[91] |
TGF-β | TGF-βR | Fu et al[92] |
CTLA-4 | CD80/CD86 | Chen et al[93] |
CD39-CD73 | ATP | Chen et al[94] |
IL-2 Rα (CD 25) | IL-2 | Li et al[95] |
LAG3 | MHC class IImolecules | Cabrera et al[96] |
Treg recruitment in HCC | Ref. | |
Molecule | Receptor | |
CCL22 | CCR4 | Li et al[97] |
CCL5 | CCR5 | Cheng et al[98] |
CCL28 | CCR3, CCR10 | Singh et al[99] |
- Citation: Granito A, Muratori L, Lalanne C, Quarneti C, Ferri S, Guidi M, Lenzi M, Muratori P. Hepatocellular carcinoma in viral and autoimmune liver diseases: Role of CD4+ CD25+ Foxp3+ regulatory T cells in the immune microenvironment. World J Gastroenterol 2021; 27(22): 2994-3009
- URL: https://www.wjgnet.com/1007-9327/full/v27/i22/2994.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i22.2994